Vincent Kompany’s men will be out to build on their morale boosting 2-1 win against Brentford prior to the break.
Coupled with Nottingham Forest’s points deduction, it saw the gap to safety reduce to just five points – giving the Clarets plenty to play for during the final nine games of the campaign.
They will be without the ineligible David Fofana at Stamford Bridge, while Ameen Al-Dakhil, Jordan Beyer, Han-Noah Massengo, Aaron Ramsey, Luca Koleosho and Nathan Redmond are all likely to remain sidelined.
With that in mind, here’s how we think the Clarets could line up:
1. GK - Arijanet Muric
After impressing on his Premier League debut prior to the international break, Muric deserves to keep hold of the shirt. Photo: Jan Kruger
2. RB - Lorenz Assignon
The Frenchman has made the right-back berth his own since arriving on loan during the January transfer window. Photo: Matt McNulty
3. CB - Dara O'Shea
The Irishman should be fit to continue at the heart of Burnley's defence after returning from international duty. Photo: Jan Kruger
4. CB - Maxime Esteve
Esteve and Dara O'Shea have enjoyed a run of games playing together at centre-back. Photo: Matt McNulty