Clitheroe have still to take a point from their travels to Farsley after another defeat at their bogey ground on Saturday.
There was a different look to the side, with Adam Reid, on loan from Altrincham, coming in as keeper, and with neither Lloyd Dean nor Sean Miller available, George Conway and Scott Bakkor were up front.
Clitheroe played down the slope in the first half, but Farsley had much of the early play, with a flurry of corners in the first 10 minutes.
From one flag kick, the ball fell loose to a home forward, who thumped it narrowly over.
The Blues’ first chance came on 16 minutes, when Andy Griffiths linked up with Conway, whose cross was met cleanly by Bakkor, but his header was turned round the post for a corner.
Midway through the half, Conway latched onto a through ball, but in rounding the keeper, pushed it too far and it went out of play.
A minute later he made amends, when a great combination down the left wing saw James Walker feed the overlapping Darren Thornton, whose cross was controlled by Conway before he slotted it calmly home.
Farsley took this in their stride and only a great blocking tackle by Will James kept the home forward at bay.
Shortly after, a superb cross from the left was met perfectly but the glancing header went just wide.
Just after the half hour, Danny Morton lost possession and Aiden Savory was clinical to draw the home side level.
Clitheroe ended the half the brighter, but Farsley started the second period with great purpose and never took their foot off the gas.
The hosts had a number of clear chances before Adam Priestley slotted home after some pin ball in the box on 65 minutes.
Farsley added a third goal on 72 minutes as a hopeful punt from halfway was not dealt with and the bouncing ball was stabbed home by Savory.
And it was 4-1 nine minutes from time when a cross from the left was met by the sliding leg of Danny Hull.